藏波罗花的化学成分研究
投稿时间:2009-06-20    责任编辑:  点此下载全文
引用本文:傅予,白央,达娃卓玛,白冰如,丁立生.藏波罗花的化学成分研究[J].中国中药杂志,2010,35(1):58.
DOI:10.4268/cjcmm20100112
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作者中文名作者英文名单位中文名单位英文名E-Mail
傅予 FU Yu 中国科学院 成都生物研究所, 四川 成都 610041 Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China  
白央 BAI Yang 西藏自治区食品药品检验所, 西藏 拉萨 850000 Tibet Autonomous Region Institute for Food and Drug Control, Lhasa 850000, China  
达娃卓玛 DAWA Zhuoma 西藏自治区食品药品检验所, 西藏 拉萨 850000 Tibet Autonomous Region Institute for Food and Drug Control, Lhasa 850000, China  
白冰如 BAI Bingru 中国科学院 成都生物研究所, 四川 成都 610041 Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China  
丁立生 DING Lisheng 中国科学院 成都生物研究所, 四川 成都 610041 Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China lsding@cib.ac.cn 
基金项目:国家自然科学基金项目(30572254)
中文摘要:目的: 对藏药材藏波罗花Incarvillea younghusbandii 的化学成分进行分离纯化和结构鉴定。 方法 :采用正反相硅胶柱色谱和Sephadex LH-20 凝胶柱色谱方法进行分离纯化,NMR和MS等波谱方法进行结构鉴定。 结果 :从藏波罗花的地上部分甲醇提取物中共分离鉴定出15个化合物:异佛手柑内酯 ( 1 ),6-甲氧基当归素 ( 2 ),欧前胡素 ( 3 ),花椒毒内酯 ( 4 ),珊瑚菜内酯 ( 5 ),heraclenol ( 6 ),rivulobirin A ( 7 ),齐墩果酸甲酯 ( 8 ),咖啡酸甲酯( 9 ),银桦酸 ( 10 ),boschniakinic aci d (11 ),tert-O-β-D-glucopyranosyl-(R)-heraclenol ( 12 ),5-methoxy-8-O-β-D-glucopyranosyloxypsoralen ( 13 ),1'-O-β-D-glucopyranosyl-3-hydroxynodakenetin ( 14 )和苯乙醇-O-β-D-吡喃葡萄糖-(1→2)-β-D-吡喃葡萄糖苷 ( 15 )。 结论 :上述化合物均为首次从该植物中分离得到,主要成分为呋喃香豆素类化合物。
中文关键词:藏波罗花  化学成分  香豆素
 
Chemical constituents of Incarvillea younghusbandii
Abstract:Objective : To study the chemical constituents of Incarvillea younghusbandii. Method : The chemical constituents were isolated by various column chromatographic methods and structurally identified by NMR and MS evidence. Result : Fifteen compounds were obtained and identified as isobergapten ( 1 ), sphondin ( 2 ), imperatorin ( 3 ), xanthotoxin ( 4 ), phellopterin ( 5 ), heraclenol ( 6 ), rivulobirin A ( 7 ), methyl oleanolate ( 8 ), methyl caffeate ( 9 ), grevillic acid ( 10 ), boschniakinic acid ( 11 ), tert-O-β-D-glucopyranosyl-(R)-heraclenol ( 12 ), 5-methoxy-8-O-β-D-glucopyranosyloxypsoralen ( 13 ), 1'-O-β-D-glucopyranosyl-3-hydroxynodakenetin ( 14 ) and phenylethyl-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside ( 15 ). Conclusion :All of these compounds were isolated from this plant for the first time and most of them are furocoumarins.
keywords:Incarvillea younghusbandii  chemical constituent  furocoumarin
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