淫羊藿苷药理作用研究进展
投稿时间:1900-01-01  修订日期:1900-01-01  责任编辑:  点此下载全文
引用本文:李娌,王学美.淫羊藿苷药理作用研究进展[J].中国中药杂志,2008,33(23):2727.
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李娌  王学美
北京大学 第一医院 中西医结合研究室, 北京 100034
中文摘要:淫羊藿苷是一种黄酮类化合物,在体内分布较为广泛,可通过血脑屏障。单体状态时符合开放型二室模型。复方状态时,复方中的其他成分对ICA有促进吸收和分布。体内主要代谢产物为其苷元。以往有大量关于淫羊藿苷对免疫系统、肿瘤组织以及生殖、内分泌系统作用的研究,证实了其强大的药理活性。近年来对于淫羊藿苷的药理研究集中在其对骨组织、心血管系统和神经系统作用等机制方面。
中文关键词:淫羊藿苷  免疫系统  肿瘤  神经系统
 
Progress of pharmacological research on icariin
LI Li; WANG Xue-mei*
Department of Integrated Chinese and Western Medicine, First Hospital, Peking University, Beijing 100034, China
Abstract:Icariin (ICA), as one of the flavones compounds, possess strong pharmacological effects. With wide body distribution, it even could pass through blood-brain barrier into brain tissues. When intaken as a pure compound, distribution of ICA in body was accord with open type of two compartment model. If it is one ingredient of a complex prescription, other component of these could promote the absorption and distribution of ICA. After metabolism, the main component left was its aglycone. A lot of research about ICA based on immunology, phymatology, genesiology and endocrinology sustained it was a valuable compounds. Recently more research about ICA concentrated their interesting to its mysterious effect on bone tissues, cardiovascular system and especially nervous systems.
keywords:icariin  immune system  tumor  nervous systems
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