全国资源普查女贞子药材质量特征关系探究及对《中国药典》女贞子药材标准规定的思考
投稿时间:2018-04-25  修订日期:2018-05-14  责任编辑:  点此下载全文
引用本文:
DOI:
摘要点击次数: 310
全文下载次数: 0
                       
作者中文名作者英文名单位中文名单位英文名E-Mail
刘欢 Liu Huan 北京中医药大学中药学院
中国食品药品检定研究院中药民族药检定所
Beijing University of Chinese Medicine 1432191881@qq.com 
熊慧 Xiong Hui 北京中医药大学中药学院 Beijing University of Chinese Medicine 1466171929@qq.com 
薛雪 Xue Xue 北京中医药大学中药学院 Beijing University of Chinese Medicine  
刘梦楠 Liu Mengnan 北京中医药大学中药学院 Beijing University of Chinese Medicine  
王海丽 Wang Haili 北京中医药大学中药学院 Beijing University of Chinese Medicine  
刘薇 Liu Wei 中国食品药品检定研究院中药民族药检定所 China National Food and Drug Testing Institute  
魏锋 Wei Feng 中国食品药品检定研究院中药民族药检定所 China National Food and Drug Testing Institute  
李向日* Li Xiangri 北京中医药大学中药学院 Beijing University of Chinese Medicine lixiangri@sina.com 
基金项目:]:名贵中药资源可持续利用能力建设(2060302)。[
中文摘要:【】:本实验采用HPLC同时测定酪醇、红景天苷、松果菊苷、芦丁、毛蕊花糖苷、女贞苷、特女贞苷、槲皮素含量,用比色卡对照法确定女贞子颜色,果实百粒重用称量法称定。采用相关性分析、单因素方差分析等统计学方法分析女贞子药材的性状、化学成分、采收时间及地理位置之间的关系,综合评价女贞子药材质量。结果显示,92%女贞子药材符合药典标准,颜色偏褐色的女贞子中7种成分(除槲皮素)含量高于颜色偏黑色的药材;6月份采收的女贞子中红景天苷含量达到最高,8-10月采收的女贞子中其他7种成分含量相对较高;根据女贞子质量参数并未能将6个产地女贞子药材有效区分。本实验结果表明,女贞子药材颜色、采收季节与成分含量之间存在一定的关系,产地与女贞子质量参数无关。本研究以期为本土女贞子药材资源现状提供一定的数据支持,为今后女贞子药材标准的修订提供理论依据。
中文关键词:女贞子  性状  化学成分  《中国药典》  采收时间  地理位置
 
A study on the quality characteristics of Ligustri lucidum in national resource survey and consideration on the standards of Ligustrum lucidum in Chinese Pharmacopoeia
Abstract:The content of tyrosol, salidroside, echinacoside, Rutinum, acteoside, ligustroflavone, specnuezhenide,and quercetin were determined by HPLC in the experiment, and the color of Ligustrum lucidum was determined by comparison with color card. Hundred-seed weight was analyzed by using gravimetric method. The correlation analysis and 0ne-Way ANOVA were used to analyze the relationship between the characters, the chemical composition, the harvest time and the geographical location of Ligustrum lucidum, for giving a comprehensive evaluation of the quality of Ligustrum lucidum. The results showed that 92 % of Ligustrum lucidum were all up to quality standard of Chinese Pharmacopoeia, and the contents of 7 components in Ligustrum lucidum (except quercetin) were higher than that in black colors. The content of Salidroside in Ligustrum lucidum harvested in June was the highest and the other 7 components of Ligustrum lucidum were relatively high in 8-10 months. According to the quality parameters of Ligustrum lucidum, the Ligustrum lucidum from six habitats can not be distinguished effectively. The results showed that there was a certain relationship between the color, harvest season and component content of Ligustrum lucidum, and the habitats were not related to the quality parameters of Ligustrum lucidum. The purpose of this study is to provide data support for the resource status of native Ligustri lucidum, and to provide a theoretical basis for the revision of standards of Ligustrum lucidum in the future.
keywords:Ligustrum lucidum  Character  Chemical composition  Chinese Pharmacopoeia  Harvest time  Geographical location
查看全文   下载PDF阅读器
相关阅读
评论
zuo-jiat you-jiat